About Placenta Injections
Placenta injections have gained increasing attention in recent years for their potential benefits in beauty enhancement and overall wellness. While many people are interested, the variety of information available can be overwhelming or even confusing.
This guide explains the benefits, drawbacks, and safety considerations of placenta injections based on scientific and historical knowledge.
What Is Placenta?
“Placenta” refers to the organ that connects a developing fetus to the mother, supplying nutrients and oxygen. It is a life-sustaining structure, rich in amino acids, vitamins, minerals, growth factors, and other essential nutrients.
Animal-derived placenta is usually obtained from healthy pigs or horses after natural full-term delivery. Only the internal placental tissue is used—excluding the uterus or external reproductive organs.
Placenta extract refers to a liquid or paste form of the placenta that has been broken down and heat-sterilized using specialized methods.
A Brief History of Placenta Use
Placenta has been used for beauty and health purposes since ancient times:
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Cleopatra is said to have used it to preserve her youthful appearance.
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Qin Shi Huang, the first emperor of China, reportedly used placenta as a longevity tonic (known as shikasha in traditional Chinese medicine).
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Hippocrates also reportedly recognized its medicinal properties.
In the late 19th century, Russian scientist Dr. Filatov began studying placenta for its regenerative potential. Modern clinical research began from that point, eventually leading to Japan’s development of medical-grade placenta treatments. Today, placenta injections are also widely used in aesthetic medicine and supplements.
Why Placenta Injections Are Gaining Popularity
Placenta is rich in nutrients like amino acids, vitamins, minerals, and growth factors. In clinical settings, injections are used to deliver these active ingredients directly into the body, aiming for effects such as:
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Improved skin condition – Promotes cell turnover, reduces dark spots and wrinkles, and improves skin elasticity and glow.
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Fatigue recovery – Enhances metabolism and reduces physical fatigue.
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Menopause relief – Helps regulate hormones, alleviating hot flashes, irritability, and mood swings.
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Liver function support – Aids in detoxification and liver health.
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Immune system enhancement – Strengthens the body's defenses against illness.
In Japan, placenta injections are covered by health insurance for women aged 45–59 when used to treat menopausal symptoms.
Placenta for Menopause Relief
Placenta contains various bioactive compounds that work together to ease menopause symptoms:
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Hormone regulation – Assists in balancing estrogen levels, reducing hot flashes and mood swings.
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Autonomic nervous system support – Helps improve symptoms like insomnia and dizziness.
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Fatigue reduction – Nutrients like amino acids and vitamins stimulate metabolism for better energy levels.
⚠️ Note: Side effects may include injection site pain, swelling, or allergic reactions. Effects can vary from person to person, so it’s important to consult a doctor before beginning treatment.
Types of Placenta
Placenta is generally categorized into two types:
1. Animal-Derived Placenta (most common)
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Human placenta: Used in prescription medications in some countries.
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Porcine (pig) placenta: Widely used in cosmetics and supplements due to its affordability and availability.
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Equine (horse) placenta: Rich in amino acids and known for premium skincare.
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Ovine (sheep) placenta: High-quality, often used in anti-aging products.
2. Plant-Based Placenta
Though not true placenta, some plant-derived extracts (like soy isoflavones) mimic similar effects and are labeled as "plant placenta." These products are suitable for those with allergies or sensitivities to animal products.
Placenta Extraction Methods
There are six major methods for extracting placenta components:
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Enzymatic hydrolysis
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Hydrochloric acid hydrolysis
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Alkaline extraction
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Freeze-thaw method
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Purified water extraction
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Hot water extraction
These processes extract valuable compounds like proteins, peptides, amino acids, nucleic acids, and sugars.
One challenge during extraction is avoiding the Maillard reaction, a chemical process between sugars and amino acids when heated. This reaction can darken the extract and degrade active ingredients. Medical-grade placenta injections are produced using strictly controlled processes to prevent this and ensure potency and safety.
